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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1997-5-9
|
| pubmed:abstractText |
From September 1989 to February 1993, 11 patients with localized adenocarcinoma of the prostate were treated with pelvic external-beam radiation therapy followed by high dose rate (HDR) transurethral brachytherapy as a boost dose. External-beam radiation therapy was administered through opposed pelvic fields using a 60Co teletherapy unit to a tumor dose of 46-50 Gy in 23-25 fractions and followed by three fractions of transurethral brachytherapy, delivered using a 60Co HDR remote afterloading equipment. The treatment time was calculated using the prostatic capsule as the reference point. The dose calculated to be delivered to the capsule was 5 Gy/fraction, making a total of 15 Gy. The follow-up period ranged from 11 to 65 months, with a median follow-up time of 30 months. Local control was achieved in all patients. The prostate-specific antigen levels were normalized within 3 months of radiotherapy in 9 patients and within 3-6 months in the remaining 2. Transurethral brachytherapy appears to be a simple and feasible form of brachytherapy. Preliminary local control and radiotherapy-related morbidity rates are comparable to those of other forms of brachytherapy. Further follow-up is required for assessment of long-term local control and delayed radiotherapy-related morbidity.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0042-1138
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
58
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
30-3
|
| pubmed:dateRevised |
2006-10-30
|
| pubmed:meshHeading |
pubmed-meshheading:9058517-Adenocarcinoma,
pubmed-meshheading:9058517-Aged,
pubmed-meshheading:9058517-Brachytherapy,
pubmed-meshheading:9058517-Cobalt Radioisotopes,
pubmed-meshheading:9058517-Follow-Up Studies,
pubmed-meshheading:9058517-Humans,
pubmed-meshheading:9058517-Male,
pubmed-meshheading:9058517-Middle Aged,
pubmed-meshheading:9058517-Prostate-Specific Antigen,
pubmed-meshheading:9058517-Prostatectomy,
pubmed-meshheading:9058517-Prostatic Neoplasms,
pubmed-meshheading:9058517-Radioisotope Teletherapy,
pubmed-meshheading:9058517-Radiotherapy Dosage,
pubmed-meshheading:9058517-Time Factors
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
High dose rate transurethral brachytherapy as a boost dose for localized adenocarcinoma of the prostate.
|
| pubmed:affiliation |
Department of Radiation Oncology, Ankara University Faculty of Medicine, Turkey.
|
| pubmed:publicationType |
Journal Article
|