Linked Life Data

9056083

Source:http://linkedlifedata.com/resource/pubmed/id/9056083

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-7-8
pubmed:abstractText
Genetically mediated sensitivity to the bitter taste of 6-n-propylthiouracil (PROP) has been associated with greater acuity for bitter and for some sweet tastes. Thus far, few studies have explored the relationship between PROP taste sensitivity and hedonic responses to bitter and sweet. In this study, 87 normal-weight young women were divided into PROP non-tasters (n = 18), regular tasters (n = 49), and supertasters (n = 20), based on their PROP detection thresholds and the scaling of five suprathreshold solutions of PROP and NaCl. Non-tasters had thresholds > 1.8 x 10(-4) mol/l PROP. Supertasters had thresholds < 3.2 x 10(-5) mol/l PROP and PROP/NaCl ratios > 1.70. As expected, dislike of the bitter taste of PROP was determined by its perceived intensity, which was greater among supertasters than among regular tasters or non-tasters. Significant correlations were observed between PROP taste thresholds and the sum of intensity ratings (r = -0.61) and between summed intensity and summed hedonic ratings (r = -0.80). PROP taste sensitivity was weakly linked to enhanced perception of sweet taste, but did not predict hedonic responses to sucrose or to saccharin solutions. Given that the dislike of PROP solutions is determined by their perceived intensity, hedonic responses to PROP solutions may provide a rapid way of screening for PROP taster status.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0379-864X
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
27-37
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Genetic sensitivity to 6-n-propylthiouracil (PROP) and hedonic responses to bitter and sweet tastes.
pubmed:affiliation
Human Nutrition Program, School of Public Health, University of Michigan, Ann Arbor 48109-2029, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.