|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003250,
umls-concept:C0003855,
umls-concept:C0004057,
umls-concept:C0012984,
umls-concept:C0019134,
umls-concept:C0026336,
umls-concept:C0032191,
umls-concept:C0038257,
umls-concept:C0040053,
umls-concept:C0225984,
umls-concept:C0336636,
umls-concept:C0597357,
umls-concept:C0684204,
umls-concept:C1280500,
umls-concept:C2348480
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|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1997-4-3
|
|
pubmed:abstractText |
Thrombosis is an important limitation of metallic coronary stents, especially in smaller vessels in which shear rates are high. Monoclonal antibody to platelet glycoprotein IIb/IIIa receptor (7E3) has been shown to inhibit shear-induced platelet aggregation. In this study, we compared the effects of 7E3, heparin, and aspirin on stent thrombosis in an ex vivo arteriovenous shunt model of high-shear blood flow.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
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pubmed:month |
Feb
|
|
pubmed:issn |
0009-7322
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
18
|
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pubmed:volume |
95
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1015-21
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9054765-Analysis of Variance,
pubmed-meshheading:9054765-Animals,
pubmed-meshheading:9054765-Antibodies, Monoclonal,
pubmed-meshheading:9054765-Arteriovenous Shunt, Surgical,
pubmed-meshheading:9054765-Aspirin,
pubmed-meshheading:9054765-Bleeding Time,
pubmed-meshheading:9054765-Coronary Vessels,
pubmed-meshheading:9054765-Dogs,
pubmed-meshheading:9054765-Extracorporeal Circulation,
pubmed-meshheading:9054765-Heparin,
pubmed-meshheading:9054765-Immunoglobulin Fab Fragments,
pubmed-meshheading:9054765-Microscopy, Electron, Scanning,
pubmed-meshheading:9054765-Platelet Aggregation,
pubmed-meshheading:9054765-Platelet Aggregation Inhibitors,
pubmed-meshheading:9054765-Platelet Glycoprotein GPIIb-IIIa Complex,
pubmed-meshheading:9054765-Stents,
pubmed-meshheading:9054765-Thrombosis,
pubmed-meshheading:9054765-Whole Blood Coagulation Time
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|
pubmed:year |
1997
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pubmed:articleTitle |
Effects of GP IIb/IIIa receptor monoclonal antibody (7E3), heparin, and aspirin in an ex vivo canine arteriovenous shunt model of stent thrombosis.
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pubmed:affiliation |
Department of Medicine, Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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