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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1997-3-31
|
| pubmed:abstractText |
Bioassay-guided isolation procedures using human tumor cell lines led to isolation of dibromophakellstatin (4) from the Republic of Seychelles sponge Phakellia mauritiana. The isolation, X-ray crystal structure elucidation, absolute stereochemistry, and antineoplastic activity have been summarized. P. mauritiana was also found to contain dibromophakellin (1), debromohymenialosine (2), thymidine, deoxyuridine, and thymine.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0163-3864
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
60
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
180-3
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:9051914-Animals,
pubmed-meshheading:9051914-Antineoplastic Agents,
pubmed-meshheading:9051914-Crystallography, X-Ray,
pubmed-meshheading:9051914-Drug Screening Assays, Antitumor,
pubmed-meshheading:9051914-Humans,
pubmed-meshheading:9051914-Imidazoles,
pubmed-meshheading:9051914-Molecular Structure,
pubmed-meshheading:9051914-Porifera,
pubmed-meshheading:9051914-Tumor Cells, Cultured
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Antineoplastic agents. 362. Isolation and X-ray crystal structure of dibromophakellstatin from the Indian ocean sponge Phakellia mauritiana.
|
| pubmed:affiliation |
Department of Chemistry, Arizona State University, Tempe 85287-2404, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|