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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1997-4-2
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pubmed:abstractText |
18-Hydroxy-11-deoxycorticosterone forms a non-polar dimer under acidic conditions. The dimer was purified by high performance liquid chromatography and further analysed by electrospray mass spectrometry. The purified dimer has a molecular weight of 656 Da with two free ketone groups and no free hydroxyl functions. The mass spectrometric data suggest a 20,21,20',21'-anhydro dimer structure for the dimer. Microbore high performance liquid chromatography/electrospray mass spectrometry of rat adrenal extracts indicated that both 18-OH-B and 18-OH-DOC were present, although no 18-OH-DOC dimer was detected.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0951-4198
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
219-23
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pubmed:dateRevised |
2009-9-29
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pubmed:meshHeading |
pubmed-meshheading:9050267-Adrenal Cortex Hormones,
pubmed-meshheading:9050267-Adrenal Glands,
pubmed-meshheading:9050267-Animals,
pubmed-meshheading:9050267-Chromatography, High Pressure Liquid,
pubmed-meshheading:9050267-Electrochemistry,
pubmed-meshheading:9050267-Mass Spectrometry,
pubmed-meshheading:9050267-Rats,
pubmed-meshheading:9050267-Rats, Wistar
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pubmed:year |
1997
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pubmed:articleTitle |
Electrospray mass spectrometric characterization of a corticosteroid dimer.
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pubmed:affiliation |
Department of Clinical Pharmacology, Royal Postgraduate Medical School, London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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