Linked Life Data

9049749

Source:http://linkedlifedata.com/resource/pubmed/id/9049749

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-6-5
pubmed:abstractText
The prevalence of cardiovascular disease (CVD) increases with advancing age in women, particularly after menopause. CVD risk is lower in physically active women relative to their sedentary peers, but the responsible mechanisms are not well understood. The aims of this study were to test the hypotheses that 1) physically active postmenopausal women demonstrate more favorable blood pressure (BP)-related risk factors for CVD than do sedentary healthy women and 2) women on hormone replacement therapy (HRT) also have more favorable levels of these CVD risk factors. BP-related CVD risk factors were measured in physically active women (n = 18; age 55 +/- 1 yr; n = 8 on HRT) and in healthy less-active controls (n = 34; age 59 +/- 1 yr; n = 17 on HRT). Maximal oxygen consumption was higher in the active group, whereas waist-to-hip ratio and waist circumference were lower (all P < 0.005). The active women demonstrated marginally lower (5-8 mmHg; P < or = 0.10) levels of casual, 24-h, and daytime systolic BP (SBP). They also tended to have lower (P = 0.11) daytime SBP loads (percentage of BP recordings > 140/90 mmHg) and lower daytime and nighttime BP variabilities (P = 0.04) and a reduced (P < 0.007) SBP response to submaximal exercise. Women on HRT tended to have lower (3-4 mmHg; P = 0.07) levels of 24-h and nighttime diastolic BP (DBP) relative to the nonusers and smaller (P < 0.04) daytime and 24-h DBP loads. Stepwise multiple regression indicated that waist circumference was the primary predictor of most of the SBP-related CVD risk factors while HRT use was the best predictor for DBP loads. These findings indicate that, in general, physically active postmenopausal women demonstrate more favorable SBP-related CVD risk factors relative to their less-active healthy peers, which may be mediated, in party, by their lower levels of abdominal adiposity. In addition, HRT use tends to be associated with lower levels of DBP-related CVD risk factors.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
8750-7587
pubmed:author
pubmed:issnType
Print
pubmed:volume
82
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
652-60
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Blood pressure risks factors in healthy postmenopausal women: physical activity and hormone replacement.
pubmed:affiliation
Department of Kinesiology, University of Colorado, Boulder 80309, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't