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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1976-10-20
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pubmed:abstractText |
Gamma-Glutamyl transpeptidase activity in guinea pig intestine was tested toward 8 monoglutamyl and 4 diglutamyl substrates. Distinct differences in specificity and activity related to ontogenetic development were noted. A mixture of L-serine and borate inhibited specifically gamma-glutamyl transpeptidase activity of homogenates and accumulation of naphthylamine and 14C-substances in slices of intestine incubated with gamma-L-14C-glutamyl-alpha-naphthylamide. The same mixture, administered per os together with 14C-gamma-glutamyl substrate, specifically inhibited urinary excretion of 14C-substance, but had no effect on the rate of excretion of glycine, L-glutamic acid or L-pyroglutamic acid.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0004-069X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
451-8
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:9046-Age Factors,
pubmed-meshheading:9046-Animals,
pubmed-meshheading:9046-Borates,
pubmed-meshheading:9046-Female,
pubmed-meshheading:9046-Guinea Pigs,
pubmed-meshheading:9046-Intestinal Mucosa,
pubmed-meshheading:9046-Male,
pubmed-meshheading:9046-Serine,
pubmed-meshheading:9046-gamma-Glutamyltransferase
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pubmed:year |
1976
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pubmed:articleTitle |
Specificity and inhibition of gamma-glutamyl transpeptidase in guinea pig intestines.
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pubmed:publicationType |
Journal Article
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