Linked Life Data

9044031

Source:http://linkedlifedata.com/resource/pubmed/id/9044031

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-5-15
pubmed:abstractText
Exposure of Staphylococcus aureus and Escherichia coli strains to different subMICs of cefodizime, cefotaxime and ceftriaxone significantly reduced the bacterial attachment to human buccal cells, but the resultant patterns of inhibition were different for S. aureus and E. coli and for the behaviour of the three cephalosporins. Morphological anomalies such as clusters of enlarged S. aureus cells and filamentation with spheroplast-like structures and bulge formations in E. coli were also present. Analogies between the different patterns of inhibition of adhesiveness and the corresponding degree of morphological changes were observed. Cefodizime behaved differently from cefotaxime and ceftriaxone and this could be attributed to the presence in the cefodizime molecule of an additional substituent, a 3-methyl-5-carboxymethyl-1,3-thiazole-2-thio group in the 3' position, not present in cefotaxime or ceftriaxone.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0305-7453
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
79-84
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Cefodizime: effects of sub-inhibitory concentrations on adhesiveness and bacterial morphology of Staphylococcus aureus and Escherichia coli: comparison with cefotaxime and ceftriaxone.
pubmed:affiliation
Centre for Respiratory Pharmacology, School of Medicine, University of Milan, Italy.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't