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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1997-4-29
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pubmed:databankReference |
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pubmed:abstractText |
Interleukin-10 (IL-10) has been described as an anti-inflammatory cytokine and B-cell proliferation factor and has been implicated in autoimmunity, tumorigenesis and transplantation tolerance. We have identified three single base pair substitutions in the IL-10 gene promoter and have investigated whether this polymorphism correlates with IL-10 protein production in vitro.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0960-7420
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:9043871-Cells, Cultured,
pubmed-meshheading:9043871-Cytokines,
pubmed-meshheading:9043871-Gene Expression Regulation,
pubmed-meshheading:9043871-Gene Frequency,
pubmed-meshheading:9043871-Humans,
pubmed-meshheading:9043871-Interleukin-10,
pubmed-meshheading:9043871-Lymphocytes,
pubmed-meshheading:9043871-Molecular Sequence Data,
pubmed-meshheading:9043871-Polymorphism, Genetic,
pubmed-meshheading:9043871-Promoter Regions, Genetic,
pubmed-meshheading:9043871-Sequence Analysis, DNA
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pubmed:year |
1997
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pubmed:articleTitle |
An investigation of polymorphism in the interleukin-10 gene promoter.
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pubmed:affiliation |
Tissue Typing Laboratory, St Mary's Hospital, Manchester, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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