Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-6-2
pubmed:abstractText
The effect of aging on the free-running period (TauDD) of a circadian rhythm for wheel-running activity was observed in two inbred strains (DBA/ 2J and C57BL/6J) and one outbred strain (Tac: (SW)fBR) of laboratory mice (Mus musculus). TauDD in the DBA and C57 mice was monitored at approximately age 100 days and age 300 days. TauDD in the outbred strain was monitored at approximately age 100 days and age 600 days. TauDD increased with age in all three strains. Most studies of age effects in rodent species have shown a shortening of TauDD with age, with th exception of the C57BL inbred mice. These results show that the lengthening of TauDD with age in laboratory mice is not limited to the C57BL strain and may be a general characteristic of this species, in contrast to other rodent species examined.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0742-0528
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
19-23
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Aging lengthens TauDD in C57BL/6J, DBA/2J, and outbred SWR male mice (Mus musculus).
pubmed:affiliation
Department of Veterans Affairs, Richard L. Roudebush Medical Center, Indianapolis, Indiana, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't