Linked Life Data

9042531

Source:http://linkedlifedata.com/resource/pubmed/id/9042531

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-5-14
pubmed:abstractText
After acquisition of a conditioned taste aversion (CTA) against sucrose, intraoral infusions of sucrose induce c-Fos-like immunoreactivity (c-FLI) in the medial intermediate nucleus of the solitary tract (iNTS) of the rat. In order to determine if c-FLI expression in the iNTS depends on subdiaphragmatic vagal afferent input to the NTS secondary to gastrointestinal symptoms during CTA expression (e.g. diarrhea), we quantified the induction of c-FLI in the iNTS by sucrose infusions after total subdiaphragmatic vagotomy in rats with a previously acquired CTA against sucrose. Rats were conditioned against infusions of sucrose by pairing sucrose infusions with toxic LiCl injections. After CTA acquisition, rats underwent bilateral subdiaphragmatic vagotomy or were sham-vagotomized. One week after surgery, rats received an intraoral infusion of sucrose. One hour after the test infusion, rats were perfused and processed for c-FLI. Vagotomy had no apparent effect on the behavioral expression of the previously acquired CTA, because both vagotomized and sham-vagotomized rats rejected all of the test intraoral infusion of sucrose. There was also no significant difference between vagotomized and sham-vagotomized rats in the number of c-FLI-positive cells in the iNTS after CTA expression. We conclude that c-FLI induction correlated with CTA expression is not dependent on subdiaphragmatic vagal efferent output or afferent input.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
747
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
85-91
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Subdiaphragmatic vagotomy does not attenuate c-Fos induction in the nucleus of the solitary tract after conditioned taste aversion expression.
pubmed:affiliation
E.W. Bourne Behavioral Research Laboratory, Department of Psychiatry, Cornell University Medical College, White Plains, NY 10605, USA. tah2@cornell.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't