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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9050
|
| pubmed:dateCreated |
1997-3-13
|
| pubmed:abstractText |
Chemokines are a family of structurally related proteins that share the ability to induce migration of specific subsets of leucocytes. These specialised cytokines play a critical part in the generation of cellular inflammation, both in the protective responses to invading pathogens and in the pathological processes associated with infection and immune-mediated diseases. Chemokines are more than simple chemotactic factors, since they are also implicated in leucocyte activation, angiogenesis, and antimicrobial functions, including a protective role in HIV infection. These molecules provide potentially valuable targets for therapeutic intervention in a wide range of diseases.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0140-6736
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
349
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
490-5
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:9040590-Chemokines,
pubmed-meshheading:9040590-Chemotactic Factors,
pubmed-meshheading:9040590-Chemotaxis, Leukocyte,
pubmed-meshheading:9040590-Cytokines,
pubmed-meshheading:9040590-HIV Infections,
pubmed-meshheading:9040590-Humans,
pubmed-meshheading:9040590-Inflammation Mediators,
pubmed-meshheading:9040590-Leukocytes
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Chemokines: leucocyte recruitment and activation cytokines.
|
| pubmed:affiliation |
Liver Reseach Laboratories, University of Birmingham, Queen Elizabeth Hospital, UK. dh.adams@bham.ac.uk
|
| pubmed:publicationType |
Journal Article
|