|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
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pubmed:dateCreated |
1997-2-25
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|
pubmed:abstractText |
Cytomegalovirus (CMV) retinitis is the most common intraocular infection in patients with the acquired immunodeficiency syndrome (AIDS). If left untreated, it may lead to progressive destruction of retinal tissue and blindness. Cidofovir is a nucleotide analogue of cytosine that has potent, prolonged in vitro and in vivo activity against herpesviruses, including many CMV isolates that are resistant to ganciclovir and foscarnet.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Feb
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|
pubmed:issn |
0003-4819
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
15
|
|
pubmed:volume |
126
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
257-63
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9036797-AIDS-Related Opportunistic Infections,
pubmed-meshheading:9036797-Adolescent,
pubmed-meshheading:9036797-Adult,
pubmed-meshheading:9036797-Antiviral Agents,
pubmed-meshheading:9036797-Cytomegalovirus Retinitis,
pubmed-meshheading:9036797-Cytosine,
pubmed-meshheading:9036797-Disease Progression,
pubmed-meshheading:9036797-Female,
pubmed-meshheading:9036797-Humans,
pubmed-meshheading:9036797-Infusions, Intravenous,
pubmed-meshheading:9036797-Male,
pubmed-meshheading:9036797-Middle Aged,
pubmed-meshheading:9036797-Organophosphorus Compounds,
pubmed-meshheading:9036797-Phosphonic Acids,
pubmed-meshheading:9036797-Prospective Studies,
pubmed-meshheading:9036797-Visual Acuity
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|
pubmed:year |
1997
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|
pubmed:articleTitle |
Intravenous cidofovir for peripheral cytomegalovirus retinitis in patients with AIDS. A randomized, controlled trial.
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pubmed:affiliation |
University of California, San Francisco, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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