Linked Life Data

9035745

Source:http://linkedlifedata.com/resource/pubmed/id/9035745

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
22
pubmed:dateCreated
1997-2-26
pubmed:abstractText
We investigated the in vitro degradation of a novel degradable polymeric composite material being developed to function as a temporary replacement for trabecular bone. This material is based on a mixture of poly(propylene fumarate) cross-linked by N-vinyl-pyrrolidone and includes sodium chloride and beta-tricalcium phosphate. Using an in vitro test in simulated body fluids, the compressive strengths and compressive moduli of two composite materials increased with degradation time and remained above the minimum values acceptable for trabecular bone substitutes. A compressive strength of 21.3 (+/- 0.4) MPa and a compressive modulus of 696 (+/- 53) MPa were measured after twelve weeks for a composite material with initial strength of 18.0 (+/- 4.6) MPa and initial modulus of 113 (+/- 40) MPa. This unexpected phenomenon may prove to be useful for orthopaedic applications.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0142-9612
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2127-30
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
In vitro degradation of a poly(propylene fumarate)-based composite material.
pubmed:affiliation
Department of Orthopaedic Surgery, Wilford Hall Medical Center, Lackland Air Force Base, San Antonio, Texas, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't