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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1997-5-29
|
| pubmed:databankReference | |
| pubmed:abstractText |
We have identified the lef-1 genes from two multiple nucleopolyhedroviruses that infect natural populations of Choristoneura fumiferana. The lef-1 genes in both viruses are directly upstream and in the opposite orientation of their respective ecdysteroid UDP-glucosyltransferase (egt) genes. This gene organization pattern is similar to that found in the genomes of AcMNPV and of OpMNPV. As well, the coding regions and putative protein sequences share a high degree of similarity. Alignment of the predicted amino acid sequences of all known baculovirus lef-1 genes suggests that the LEF-1 proteins have a relatively high degree of conservation, particularly at four identified and distinct domains. Moreover, LEF-1 proteins bear clear similarity to some eukaryotic primases, predominately at three of the four domains where certain amino acids are absolutely conserved.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0920-8569
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
13
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
229-37
|
| pubmed:dateRevised |
2007-10-10
|
| pubmed:meshHeading |
pubmed-meshheading:9035367-Amino Acid Sequence,
pubmed-meshheading:9035367-Animals,
pubmed-meshheading:9035367-Baculoviridae,
pubmed-meshheading:9035367-Base Sequence,
pubmed-meshheading:9035367-Cell Line,
pubmed-meshheading:9035367-Conserved Sequence,
pubmed-meshheading:9035367-DNA Primase,
pubmed-meshheading:9035367-Eukaryotic Cells,
pubmed-meshheading:9035367-Genes, Viral,
pubmed-meshheading:9035367-Humans,
pubmed-meshheading:9035367-Molecular Sequence Data,
pubmed-meshheading:9035367-Moths,
pubmed-meshheading:9035367-Nucleopolyhedrovirus,
pubmed-meshheading:9035367-RNA Nucleotidyltransferases,
pubmed-meshheading:9035367-Sequence Analysis, DNA,
pubmed-meshheading:9035367-Sequence Homology, Amino Acid,
pubmed-meshheading:9035367-Transcription, Genetic,
pubmed-meshheading:9035367-Viral Proteins
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
The putative LEF-1 proteins from two distinct Choristoneura fumiferana multiple nucleopolyhedroviruses share domain homology to eukaryotic primases.
|
| pubmed:affiliation |
Canadian Forest Service, Sault Ste. Marie, ON, Canada.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|