Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1997-4-16
pubmed:abstractText
The laser Doppler technique and monochromatic photography were used to measure the total retinal blood flow, temporal/nasal differences in blood flow and the relationship between blood flow and vessel diameter in 5 healthy subjects, aged 54-58 years. Systemic blood pressure (BP) and intraocular pressure were also measured, and the retinal perfusion pressure was calculated. The measurements were compared to those previously obtained from a younger group of 7 healthy subjects, aged 25-38 years. Total retinal blood flow was 73 +/- 13 microliters/min in the middle-aged subjects and was not significantly different from the value measured in young subjects (80 +/- 12 microliters/min). Retinal perfusion pressure was significantly higher in the older subjects, primarily due to elevated systemic BP. The similarity in total flow between the two groups, even though the retinal perfusion pressures were higher in the older group, is an indication of an increased vascular resistance to flow. The increase may be an aging phenomenon or an indication of a well-functioning autoregulatory capacity in the retinal vasculature of the older subjects.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0030-3747
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
343-50
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Retinal hemodynamics in middle-aged normal subjects.
pubmed:affiliation
Department of Ophthalmology, Asakihawa Medical College, Japan.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.