Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-4-29
pubmed:abstractText
Lung volume reduction surgery (LVRS) is performed to alleviate dyspnoea of selected patients with severe pulmonary emphysema and to improve their pulmonary function, performance in daily activity and quality of life. By resection of destroyed lung areas the achievable improvements in function may consist of: 1) a reduction in hyperinflation resulting in amelioration of diaphragm and chest wall mechanics; 2) an increase of elastic recoil pressure, thereby augmenting expiratory flow rates; and 3) possibly an improvement in gas exchange. Meticulous selection of suitable patients, refinements in operative techniques, anaesthesiological and postoperative management has lowered perioperative mortality to less than 5% in groups who are experienced with this type of procedure. The best functional results are achieved by bilateral resection, which can either be performed by median sternotomy or by video-assisted thoracoscopy (VAT). The average increase in forced expiratory volume in one second (FEV1), obtained by bilateral resection in patients already receiving optimal medical therapy ranges 32-93%, and the reduction in hyperinflation, assessed by a decrease in total lung capacity ranges 15-20%. These favourable improvements have been reported to last in most of the patients for at least one year.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0903-1936
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
208-18
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:9032517-Activities of Daily Living, pubmed-meshheading:9032517-Anesthesia, pubmed-meshheading:9032517-Diaphragm, pubmed-meshheading:9032517-Dyspnea, pubmed-meshheading:9032517-Endoscopy, pubmed-meshheading:9032517-Follow-Up Studies, pubmed-meshheading:9032517-Forced Expiratory Volume, pubmed-meshheading:9032517-Humans, pubmed-meshheading:9032517-Lung, pubmed-meshheading:9032517-Lung Compliance, pubmed-meshheading:9032517-Patient Selection, pubmed-meshheading:9032517-Peak Expiratory Flow Rate, pubmed-meshheading:9032517-Pneumonectomy, pubmed-meshheading:9032517-Postoperative Care, pubmed-meshheading:9032517-Pressure, pubmed-meshheading:9032517-Pulmonary Emphysema, pubmed-meshheading:9032517-Pulmonary Gas Exchange, pubmed-meshheading:9032517-Quality of Life, pubmed-meshheading:9032517-Respiratory Mechanics, pubmed-meshheading:9032517-Sternum, pubmed-meshheading:9032517-Survival Rate, pubmed-meshheading:9032517-Thoracoscopy, pubmed-meshheading:9032517-Thoracotomy, pubmed-meshheading:9032517-Thorax, pubmed-meshheading:9032517-Total Lung Capacity, pubmed-meshheading:9032517-Video Recording
pubmed:year
1997
pubmed:articleTitle
Lung volume reduction surgery for emphysema.
pubmed:affiliation
Dept of Internal Medicine, University Hospital, Zurich, Switzerland.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't