Linked Life Data

9031815

Source:http://linkedlifedata.com/resource/pubmed/id/9031815

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-4-30
pubmed:abstractText
P300 event related brain potentials were studied in 49 cocaine dependent patients, abstinent for 1-5 months, and 20 healthy, non-drug-dependent controls. Patients were assigned to one of two subgroups based on the presence/absence of a DSM-IIIR diagnosis of antisocial personality disorder (ASPD). Analyses of P300s recorded during a visual selective attention task revealed reduced amplitudes at frontal electrode sites among patients with ASPD, relative to the ASPD negative patient and control groups. The frontal P300 decrement was significantly correlated with the number of childhood conduct disorder symptoms, but not with the presence/absence of a family history of alcoholism. A secondary analysis examined the relationship between P300 amplitude among cocaine dependent patients and their future behavior, i.e., relapse versus continued abstinence. Discriminant function analysis revealed that P300 amplitude alone accurately identified 70.6% of the patients who later relapsed, and 53.3% of the patients who did not.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0376-8716
pubmed:author
pubmed:issnType
Print
pubmed:day
10
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-10
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Frontal P300 decrements, childhood conduct disorder, family history, and the prediction of relapse among abstinent cocaine abusers.
pubmed:affiliation
Department of Psychiatry, University of Connecticut School of Medicine, Farmington 06030-2103, USA. bauer@psychiatry.uchc.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.