Linked Life Data

9030410

Source:http://linkedlifedata.com/resource/pubmed/id/9030410

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-4-15
pubmed:abstractText
It is known that the execution of the motor response in a simple reaction time (RT) task can be delayed by transcranial magnetic stimulation (TMS). This paper is aimed at determining the site of action where the delay in RT occurs. A delay in RT was obtained only at those TMS sites over the motor cortex contralateral to the responding hand, which produced also a muscle twitch in the responding hand. The delay in RT covaried with the TMS intensity and increased the closer the time of TMS approached the expected time of reaction onset. Visual and auditory go-signals yielded similar delays in RT, but only when TMS was applied about 40 ms later for the visual go-signal, corresponding to the modality specific difference in RT control values. TMS of the supplementary motor area (SMA) immediately prior to the expected time of reaction onset produced no delay in RT. Spinal excitability as tested by F waves showed a pre-movement facilitation in the control trials which continued seemingly undisturbed during the period of RT delay after TMS. It can be concluded that the delay in RT is not due to SMA stimulation or spinal inhibition but depends on effective stimulation of neural elements in the motor cortex which are active very late in the process of movement release from the final motor output stage.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
2
pubmed:volume
744
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
32-40
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Delay in simple reaction time after focal transcranial magnetic stimulation of the human brain occurs at the final motor output stage.
pubmed:affiliation
Department of Clinical Neurophysiology, Georg-August-University of Gttingen, Germany. u.ziemann@med.uni-goettingen.de
pubmed:publicationType
Journal Article