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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1997-3-14
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pubmed:databankReference |
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pubmed:abstractText |
We have cloned a cDNA encoding rabbit alpha 1d-adrenoceptor from the rabbit liver cDNA library. The deduced amino-acid sequence of this clone encodes a protein of 576 amino acids that shows strong sequence homology to previously cloned human, rat and mouse alpha 1d-adrenoceptors. The pharmacological radioligand binding properties of this clone expressed in COS-7 cells were similar to those of rat alpha 1d-adrenoceptors. Competitive RT/PCR assays revealed wide tissue distribution of the alpha 1d-adrenoceptor mRNA in rabbit, especially abundant in vas deferens, aorta, prostate and cerebral cortex.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ADRA1D protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Adra1d protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Complementary,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Adrenergic, alpha-1
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0006-3002
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
14
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pubmed:volume |
1323
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6-11
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:9030207-Amino Acid Sequence,
pubmed-meshheading:9030207-Animals,
pubmed-meshheading:9030207-Base Sequence,
pubmed-meshheading:9030207-COS Cells,
pubmed-meshheading:9030207-Cloning, Molecular,
pubmed-meshheading:9030207-DNA, Complementary,
pubmed-meshheading:9030207-DNA Primers,
pubmed-meshheading:9030207-Gene Expression,
pubmed-meshheading:9030207-Humans,
pubmed-meshheading:9030207-Male,
pubmed-meshheading:9030207-Mice,
pubmed-meshheading:9030207-Molecular Sequence Data,
pubmed-meshheading:9030207-Polymerase Chain Reaction,
pubmed-meshheading:9030207-RNA, Messenger,
pubmed-meshheading:9030207-Rabbits,
pubmed-meshheading:9030207-Rats,
pubmed-meshheading:9030207-Receptors, Adrenergic, alpha-1,
pubmed-meshheading:9030207-Sequence Homology, Amino Acid,
pubmed-meshheading:9030207-Tissue Distribution
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pubmed:year |
1997
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pubmed:articleTitle |
Cloning, functional expression and tissue distribution of rabbit alpha 1d-adrenoceptor.
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pubmed:affiliation |
Department of Pharmacology, Fukui Medical School, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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