Linked Life Data

9027992

Source:http://linkedlifedata.com/resource/pubmed/id/9027992

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11-12
pubmed:dateCreated
1997-5-8
pubmed:abstractText
The sea anemone Anemonia sulcata is a well-known natural source of supply of biologically active polypeptides. So far, five toxins, ATX I, II, III, IV and AS V, several polyvalent protease inhibitors, an elastase inhibitor, two blood pressure-depressive polypeptides and very recently peptides that inhibit competitively the binding of 125I-dendrotoxin to rat brain membranes and block the voltage-sensitive K+ channels, have been isolated from it. The sea anemone toxins (especially toxin II of A. sulcata, ATX II) are very important tools in neurophysiological and pharmacological research, and their structure-function relationship has been investigated. Because of the great scientific value of the sea anemone toxins a simplification of their purification procedure was elaborated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0041-0101
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1361-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
A simple biochemical method in the search for bioactive polypeptides in a sea anemone (Anemonia sulcata).
pubmed:affiliation
Institut für Toxikologie, Klinikum der Christian-Albrechts-Universität zu Kiel, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't