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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1997-3-18
|
| pubmed:abstractText |
Deleted in colorectal cancer (DCC), a candidate tumor-suppressor gene, has recently been found to encode a netrin receptor required for axon guidance in vitro. Mutations in Caenorhabditis elegans and Drosophila genes encoding DCC-related proteins affect axon guidance, and these phenotypes resemble those of mutations in netrin genes. Netrins and their DCC-related receptors thus play an evolutionarily conserved role in midline guidance, and DCC may be required more generally for cellular morphogenesis.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0959-437X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
7
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
87-92
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:9024638-Amino Acid Sequence,
pubmed-meshheading:9024638-Animals,
pubmed-meshheading:9024638-Axons,
pubmed-meshheading:9024638-Cell Adhesion Molecules,
pubmed-meshheading:9024638-Genes, DCC,
pubmed-meshheading:9024638-Humans,
pubmed-meshheading:9024638-Molecular Sequence Data,
pubmed-meshheading:9024638-Nervous System Physiological Phenomena,
pubmed-meshheading:9024638-Receptors, Cell Surface,
pubmed-meshheading:9024638-Tumor Suppressor Proteins
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
DCC's function takes shape in the nervous system.
|
| pubmed:affiliation |
823 Light Hall, Howard Hughes Medical Institute, Vanderbilt University Medical Center, Nashville, Tennessee 37232-0295, USA. kolodzp@ctrvax. vanderbilt.edu
|
| pubmed:publicationType |
Journal Article,
Review
|