|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003009,
umls-concept:C0024554,
umls-concept:C0216784,
umls-concept:C0232105,
umls-concept:C0681850,
umls-concept:C0871261,
umls-concept:C1280500,
umls-concept:C1550501,
umls-concept:C1704632,
umls-concept:C1706203,
umls-concept:C1706817,
umls-concept:C2349001,
umls-concept:C2697811,
umls-concept:C2911692
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
1997-2-27
|
|
pubmed:abstractText |
Valsartan is an oral antagonist of angiotensin II that competes with angiotensin II for the AT1-receptor and is being developed as an antihypertensive agent. This study assessed the ability of 80 mg valsartan to inhibit the pressor effect of exogenous angiotensin II in healthy normotensive men, first after a single dose and then after multiple doses once daily for 7 days.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
0009-9236
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
61
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
35-44
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:9024172-Adult,
pubmed-meshheading:9024172-Analysis of Variance,
pubmed-meshheading:9024172-Angiotensin II,
pubmed-meshheading:9024172-Antihypertensive Agents,
pubmed-meshheading:9024172-Area Under Curve,
pubmed-meshheading:9024172-Blood Pressure,
pubmed-meshheading:9024172-Cross-Over Studies,
pubmed-meshheading:9024172-Double-Blind Method,
pubmed-meshheading:9024172-Drug Administration Schedule,
pubmed-meshheading:9024172-Humans,
pubmed-meshheading:9024172-Linear Models,
pubmed-meshheading:9024172-Male,
pubmed-meshheading:9024172-Receptors, Angiotensin,
pubmed-meshheading:9024172-Reference Values,
pubmed-meshheading:9024172-Tetrazoles,
pubmed-meshheading:9024172-Time Factors,
pubmed-meshheading:9024172-Valine
|
|
pubmed:year |
1997
|
|
pubmed:articleTitle |
The effect of valsartan on the angiotensin II pressor response in healthy normotensive male subjects.
|
|
pubmed:affiliation |
Department of Medicine, Allegheny University of the Health Sciences, Philadelphia, PA 19129, USA.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|
