Linked Life Data

9021440

Source:http://linkedlifedata.com/resource/pubmed/id/9021440

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-5-28
pubmed:abstractText
In 22 individuals with a renal graft the correlations between the renal clearance of polyfructosan (CLPF), renal creatinine clearance (CLcr)--established under the same conditions as CLPF--and the value of glomerular function predicted using the equation by Cocroft and Gault (PredCLcr) were followed up, at an interval of 2-3 months, for 8-22 months. A significant linear correlation (r = 0.777, p < 0.001) was found between PredCLcr and CLPF as well as between PredCLcr and CLcr (r = 0.801, p < 0.001). Equally significant correlations, however, were established when relating the serum concentrations of creatinine (Scr) to 1/CLPF (r = 0.784, p < 0.001) and Scr to 1/CLcr (r = 0.744, p < 0.001). The values of the PredCLcr/CLPF and PredCLcr/CLcr ratios during follow-up in one and the same individual may vary significantly. This fluctuation exceeds maximal error of the analytical methods employed in one third of the individuals examined. When considering stabilization or slow changes in graft function on the basis of PredCLcr and CLPF we found significant discrepancies in more than one half of the individuals examined (64%). The findings support the assumption that more accurate methods must be used to assess graft glomerular function on long-term follow-up.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0946-1965
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
33-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Predicting glomerular function from adjusted serum creatinine in renal transplant patients.
pubmed:affiliation
Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
pubmed:publicationType
Journal Article, Clinical Trial