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pubmed-article:9021210pubmed:abstractTextTEM-1 hyperproduction in two ampicillin-sulbactam-resistant Shigella flexneri strains was studied. In both strains the blaTEM gene was encoded as a single copy on a large conjugatively transferable plasmid. A single G-->T transversion at position 1 of the -10 consensus sequence was identified to be the mechanism of TEM-1 hyperproduction.lld:pubmed
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pubmed-article:9021210pubmed:articleTitleTransferable hyperproduction of TEM-1 beta-lactamase in Shigella flexneri due to a point mutation in the pribnow box.lld:pubmed
pubmed-article:9021210pubmed:affiliationDepartment of Microbiology, Queen Mary Hospital Compound, University of Hong Kong, Hong Kong.lld:pubmed
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