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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1997-5-5
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pubmed:databankReference |
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pubmed:abstractText |
TEM-1 hyperproduction in two ampicillin-sulbactam-resistant Shigella flexneri strains was studied. In both strains the blaTEM gene was encoded as a single copy on a large conjugatively transferable plasmid. A single G-->T transversion at position 1 of the -10 consensus sequence was identified to be the mechanism of TEM-1 hyperproduction.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-1650734,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-1938685,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-2892042,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-336612,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-358200,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-3876073,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-6325162,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-6326054,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-6329713,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-6344016,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-7009583,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-7574506,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-7574532,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-7763410,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-807678,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-8132152,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-8585729,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9021210-8834898
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0066-4804
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
468-70
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:9021210-Anti-Bacterial Agents,
pubmed-meshheading:9021210-Base Sequence,
pubmed-meshheading:9021210-Colony Count, Microbial,
pubmed-meshheading:9021210-Drug Resistance, Microbial,
pubmed-meshheading:9021210-Escherichia coli,
pubmed-meshheading:9021210-Genes, Bacterial,
pubmed-meshheading:9021210-Molecular Sequence Data,
pubmed-meshheading:9021210-Plasmids,
pubmed-meshheading:9021210-Point Mutation,
pubmed-meshheading:9021210-Polymerase Chain Reaction,
pubmed-meshheading:9021210-Shigella flexneri,
pubmed-meshheading:9021210-Transformation, Bacterial,
pubmed-meshheading:9021210-beta-Lactamases
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pubmed:year |
1997
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pubmed:articleTitle |
Transferable hyperproduction of TEM-1 beta-lactamase in Shigella flexneri due to a point mutation in the pribnow box.
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pubmed:affiliation |
Department of Microbiology, Queen Mary Hospital Compound, University of Hong Kong, Hong Kong.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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