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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1979-11-21
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pubmed:abstractText |
The maturation of feline syncytium-forming virus (FSFV), a member of the foamy virus sub-family (Spumavirinae), has been studied by electron microscopy of thin sections of infected feline embryo (FEA) cells. The initial event observed was formation of crescent-shaped nucleoids at the plasma membrane. As budding progressed, the nucleoid became circular in outline with an electron-lucent centre in fully mature extracellular particles. These observations suggested that the maturation of FSFV in fully permissive FEA cells resembled that of C-type RNA tumour viruses, rather thant the B-type mouse mammary tumour virus. In this respect FSFV may be distinct from other foamy viruses. However, like other foamy viruses FSFV possessed reverse transcriptase activity. Polymerase activity co-sedimented with infectivity in an equilibrium density gradient and exhibited a preference for poly(rA).oligo(dT)10 over poly(dA).oligo(dT)10 as exogenous template.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-1317
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
429-34
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:90117-Animals,
pubmed-meshheading:90117-Cats,
pubmed-meshheading:90117-Cell Line,
pubmed-meshheading:90117-Cell Membrane,
pubmed-meshheading:90117-RNA-Directed DNA Polymerase,
pubmed-meshheading:90117-Retroviridae,
pubmed-meshheading:90117-Spumavirus,
pubmed-meshheading:90117-Virus Replication
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pubmed:year |
1979
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pubmed:articleTitle |
Feline syncytium-forming virus: identification of a virion associated reverse transcriptase and electron microscopical observations of infected cells.
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pubmed:publicationType |
Journal Article
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