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pubmed-article:9009647pubmed:abstractTextA livid, sharply defined enanthema of the oral mucosa with ulcerations on the soft palate in a patient presenting with de novo acute myeloid leukaemia with prolonged, therapy-induced granulocytopenia (< 0.5 nl-1 for 113 days!) was diagnosed as geotrichosis. Geotrichum capitatum was identified both in vivo and in vitro. Pneumonic infiltrates in the upper lobes of both lungs were treated with amphotericin B infusions. Healing of the aforementioned enanthema was only achieved after addition of 5-fluorocytosine to therapy. Susceptibility determinations with several Geotrichum capitatum isolates led to the conclusion that amphotericin B was unsuitable as a therapeutic agent in this case. 5-Fluorocytosine and itraconazole exhibited superior antifungal and antimycotic activity.lld:pubmed
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pubmed-article:9009647pubmed:dateRevised2004-11-17lld:pubmed
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pubmed-article:9009647pubmed:articleTitleGeotrichosis of oral mucosa.lld:pubmed
pubmed-article:9009647pubmed:affiliationDepartment of Dermatology, General Hospital St. Georg, Hamburg, Germany.lld:pubmed
pubmed-article:9009647pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:9009647pubmed:publicationTypeCase Reportslld:pubmed