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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7-8
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pubmed:dateCreated |
1997-2-21
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pubmed:abstractText |
A livid, sharply defined enanthema of the oral mucosa with ulcerations on the soft palate in a patient presenting with de novo acute myeloid leukaemia with prolonged, therapy-induced granulocytopenia (< 0.5 nl-1 for 113 days!) was diagnosed as geotrichosis. Geotrichum capitatum was identified both in vivo and in vitro. Pneumonic infiltrates in the upper lobes of both lungs were treated with amphotericin B infusions. Healing of the aforementioned enanthema was only achieved after addition of 5-fluorocytosine to therapy. Susceptibility determinations with several Geotrichum capitatum isolates led to the conclusion that amphotericin B was unsuitable as a therapeutic agent in this case. 5-Fluorocytosine and itraconazole exhibited superior antifungal and antimycotic activity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0933-7407
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
289-91
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9009647-Agranulocytosis,
pubmed-meshheading:9009647-Antifungal Agents,
pubmed-meshheading:9009647-Flucytosine,
pubmed-meshheading:9009647-Geotrichosis,
pubmed-meshheading:9009647-Geotrichum,
pubmed-meshheading:9009647-Humans,
pubmed-meshheading:9009647-Itraconazole,
pubmed-meshheading:9009647-Leukemia, Myeloid,
pubmed-meshheading:9009647-Male,
pubmed-meshheading:9009647-Microbial Sensitivity Tests,
pubmed-meshheading:9009647-Middle Aged,
pubmed-meshheading:9009647-Mouth Mucosa
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pubmed:articleTitle |
Geotrichosis of oral mucosa.
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pubmed:affiliation |
Department of Dermatology, General Hospital St. Georg, Hamburg, Germany.
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pubmed:publicationType |
Journal Article,
Case Reports
|