Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1997-3-11
pubmed:abstractText
To quantify the renal excretion of angiotensin II (AII) in birds, synthetic AII was intravenously infused into conscious Pekin ducks at rates of 5, 15 and 45 ng/kg/min for 30 min and the relationships between plasma and urine AII concentrations were monitored by radioimmunoassay. The infusions of AII produced dose-dependent elevations in the plasma concentrations of the hormone, however, urinary concentrations and excretion rates did not change significantly from the basal values of 11.6 +/- 1.2 pg/ml and 4.3 +/- 1.0 pg/min, respectively. The metabolic clearance rate of AII remained constant at each infusion dose (approximately 120 ml/min/kg). The urinary clearance rates (< 0.3 ml/min/kg) indicated that the fraction of AII cleared from the blood via the urine was less than 0.2%. Clearly, excretion of intact AII via this route is not a quantitatively important means of elimination for this hormone in birds.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1096-4940
pubmed:author
pubmed:issnType
Print
pubmed:volume
115
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
335-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Urinary clearance of angiotensin II in Pekin ducks.
pubmed:affiliation
Department of Physiology, University of the Witwatersrand, Johannesburg, South Africa.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't