Linked Life Data

9001146

Source:http://linkedlifedata.com/resource/pubmed/id/9001146

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-4-3
pubmed:abstractText
1H MR spectra obtained by chemical shift imaging (CSI) of contrast-enhancing brain tumors before and after the administration of Gd-contrast agent were quantitated and compared with the results in normal brain tissue included in the volume of interest. Twenty-seven combined magnetic resonance imaging and spectroscopy (MRI, MRS) examinations of brain tumor lesions included T1-weighted MRI and CSI (TR/TE 1500/135 ms double-spin echo) repeated 5-10 min after the administration of Gd-contrast agent (0.1-0.2 mM). In 1H MR spectra of contrast-enhancing tumor Gd-contrast induced a mean loss of 15% of the peak area of choline-containing compounds (Cho, P < 0.001) that was correlated with precontrast Cho linewidth (r = -0.72, P < 0.00001). This phenomenon limits the diagnostic use of brain tumor MRS examinations performed immediately after contrast-enhanced MRI.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0740-3194
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
222-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
1H chemical shift imaging reveals loss of brain tumor choline signal after administration of Gd-contrast.
pubmed:affiliation
Dr. Daniel den Hoed Cancer Center, Department of Radiology, University Hospital Rotterdam, The Netherlands.
pubmed:publicationType
Journal Article, Comparative Study