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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1997-2-13
|
| pubmed:abstractText |
In an outbred pig model of total bowel transplantation, we previously showed that simultaneous donor-specific bone marrow infusion (DSBMI), rather than promoting engraftment, sensitizes recipients and causes rejection; it also aggravates the risk of generalized graft-versus-host disease (GVHD) and infection, and tends to reduce recipient and graft survival. Small and large animal models of bone marrow-induced transplant tolerance suggest that some form of recipient preconditioning (RPC) may facilitate engraftment of co-transplanted bone marrow cells and fully expose their tolerogenic potential.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0041-1337
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
63
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
12-20
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:9000654-Animals,
pubmed-meshheading:9000654-Bone Marrow Transplantation,
pubmed-meshheading:9000654-Cause of Death,
pubmed-meshheading:9000654-Graft Rejection,
pubmed-meshheading:9000654-Graft vs Host Disease,
pubmed-meshheading:9000654-Intestines,
pubmed-meshheading:9000654-Survival Rate,
pubmed-meshheading:9000654-Swine,
pubmed-meshheading:9000654-Transplantation Conditioning
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Recipient preconditioning and donor-specific bone marrow infusion in a pig model of total bowel transplantation.
|
| pubmed:affiliation |
Department of Surgery and Biotherapy Program, University of Minnesota, Minneapolis 55455, USA.
|
| pubmed:publicationType |
Journal Article
|