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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1997-2-18
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pubmed:databankReference | |
pubmed:abstractText |
We report here the nucleotide sequence of the L gene of avian pneumovirus (APV). This is the second pneumovirus L gene and the second avian paramyxovirus L gene, following that of Newcastle disease virus, to be sequenced. The APV L gene is 6099 nucleotides long and encodes a single large ORF of 2004 amino acids. This makes the APV L protein the smallest to be described for any nonsegmented, negative-strand RNA virus. The protein contains six linear non-contiguous domains, a putative ATP-binding site and four polymerase motifs previously described for the L proteins of negative-strand RNA viruses. Phylogenetic analysis of domain III of 14 different L proteins suggests the pneumoviruses to be as distant in evolutionary terms from the other members of the Paramyxoviridae as are the Filoviridae.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0022-1317
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
77 ( Pt 12)
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3047-51
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9000096-Amino Acid Sequence,
pubmed-meshheading:9000096-Animals,
pubmed-meshheading:9000096-Base Sequence,
pubmed-meshheading:9000096-DNA, Viral,
pubmed-meshheading:9000096-Molecular Sequence Data,
pubmed-meshheading:9000096-Pneumovirus,
pubmed-meshheading:9000096-Polymerase Chain Reaction,
pubmed-meshheading:9000096-RNA, Messenger,
pubmed-meshheading:9000096-RNA, Viral,
pubmed-meshheading:9000096-Sequence Analysis, DNA,
pubmed-meshheading:9000096-Sequence Homology, Amino Acid,
pubmed-meshheading:9000096-Turkeys,
pubmed-meshheading:9000096-Viral Proteins
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pubmed:year |
1996
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pubmed:articleTitle |
Nucleotide sequence of the gene encoding the viral polymerase of avian pneumovirus.
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pubmed:affiliation |
Department of Biological Sciences, University of Warwick, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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