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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1997-2-4
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pubmed:abstractText |
Prostate cancer is an increasingly common disease for which there are few well-established risk factors. Family history data suggest a genetic component; however, the majority of prostate cancer cases cannot be explained by a single-gene model. Prostate cell division is influenced by two steroid hormones, testosterone and vitamin D, the action of each being mediated by its respective receptor. The genes for the two receptors are candidates in a multigenic model for prostate cancer susceptibility.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0027-8874
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
166-70
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8998186-Alleles,
pubmed-meshheading:8998186-Case-Control Studies,
pubmed-meshheading:8998186-Disease Susceptibility,
pubmed-meshheading:8998186-Genetic Predisposition to Disease,
pubmed-meshheading:8998186-Genotype,
pubmed-meshheading:8998186-Humans,
pubmed-meshheading:8998186-Logistic Models,
pubmed-meshheading:8998186-Male,
pubmed-meshheading:8998186-Neoplasm Staging,
pubmed-meshheading:8998186-Odds Ratio,
pubmed-meshheading:8998186-Pilot Projects,
pubmed-meshheading:8998186-Polymorphism, Genetic,
pubmed-meshheading:8998186-Prostatic Neoplasms,
pubmed-meshheading:8998186-Receptors, Androgen,
pubmed-meshheading:8998186-Receptors, Calcitriol,
pubmed-meshheading:8998186-Risk,
pubmed-meshheading:8998186-Risk Factors,
pubmed-meshheading:8998186-Trinucleotide Repeats
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pubmed:year |
1997
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pubmed:articleTitle |
Association of prostate cancer risk with genetic polymorphisms in vitamin D receptor and androgen receptor.
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pubmed:affiliation |
Department of Preventive Medicine, Norris Comprehensive Cancer Center, University of Southern California School of Medicine, Los Angeles 90033-0800, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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