Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
14
|
| pubmed:dateCreated |
1977-10-14
|
| pubmed:abstractText |
The first case of Sipple syndrome in identical twins is reported. It is concluded that the concordant medullary carcinoma of the thyroid is the result of a germinal mutation, whilst the discordant solitary phaeochromocytoma is caused by a somatic mutation according to the two mutation model. The practical conclusion to be drawn from this report is that if one identical twin develops carcinoma of the thyroid or a phaeochromocytoma, the other twin should be throughly investigated and surgical exploration undertaken, even in the absence of clinical evidence of disease.
|
| pubmed:language |
ger
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0043-5325
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
89
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
481-4
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:899022-Adult,
pubmed-meshheading:899022-Diseases in Twins,
pubmed-meshheading:899022-Female,
pubmed-meshheading:899022-Humans,
pubmed-meshheading:899022-Male,
pubmed-meshheading:899022-Parathyroid Neoplasms,
pubmed-meshheading:899022-Pheochromocytoma,
pubmed-meshheading:899022-Syndrome,
pubmed-meshheading:899022-Thyroid Neoplasms
|
| pubmed:year |
1977
|
| pubmed:articleTitle |
[Concordant medullary thyroid carcinoma in identical twins with discordant phaeochromocytoma (Sipple syndrome) (author's transl)].
|
| pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|