Linked Life Data

8987791

Source:http://linkedlifedata.com/resource/pubmed/id/8987791

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-11-28
pubmed:abstractText
The effect of superfused serotonin (5-HT; 50 microns) on the synaptic responses of the lateral giant (LG) interneuron in crayfish was found to depend on the social status of the animal. In socially isolated animals. 5-HT persistently increased the response of LG to sensory nerve shock. After social isolates were paired in a small cage, they fought and determined their dominant and subordinate status. After 12 d of pairing, 5-HT reversibly inhibited the response of LG in the social subordinate and reversibly increased the response of LG in the social dominant crayfish. The effect of 5-HT changed approximately linearly from response enhancement to inhibition in the new subordinate over the 12 d of pairing. If, after 12 d pairing, the subordinate was reisolated for 8 d, the response enhancement was restored. If the subordinate, instead, was paired with another subordinate and became dominant in this new pair, the inhibitory effect of 5-HT changed to an enhancing effect over the next 12 d of pairing. If, however, two dominant crayfish were paired and one became subordinate, the enhancing effect of 5-HT persisted in the new subordinate even after 38 d pairing. These different effects of serotonin result from the action of two or more molecular receptors for serotonin. A vertebrate 5-HT, agonist had no effect on social isolates but reversibly inhibited the response of LG in both dominant and subordinate crayfish. The inhibitory effects of the agonist developed approximately linearly over the first 12 d of pairing. A vertebrate 5-HT2 agonist persistently increased the response of LG in isolate crayfish and reversibly increased the response of the cell in dominant and subordinate crayfish. Finally, although neurons that might mediate these effects of superfused 5-HT are unknown, one pair of 5-HT-immunoreactive neurons appears to contact the LG axon and initial axon segment in each abdominal ganglion in its projection caudally from the thorax.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0270-6474
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
697-708
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:8987791-Adaptation, Physiological, pubmed-meshheading:8987791-Afferent Pathways, pubmed-meshheading:8987791-Age Factors, pubmed-meshheading:8987791-Agonistic Behavior, pubmed-meshheading:8987791-Animals, pubmed-meshheading:8987791-Astacoidea, pubmed-meshheading:8987791-Escape Reaction, pubmed-meshheading:8987791-Female, pubmed-meshheading:8987791-Ganglia, Invertebrate, pubmed-meshheading:8987791-Interneurons, pubmed-meshheading:8987791-Locomotion, pubmed-meshheading:8987791-Male, pubmed-meshheading:8987791-Mechanoreceptors, pubmed-meshheading:8987791-Piperazines, pubmed-meshheading:8987791-Receptors, Serotonin, pubmed-meshheading:8987791-Serotonin, pubmed-meshheading:8987791-Serotonin Receptor Agonists, pubmed-meshheading:8987791-Social Dominance, pubmed-meshheading:8987791-Social Isolation, pubmed-meshheading:8987791-Tail
pubmed:year
1997
pubmed:articleTitle
Neuronal adaptations to changes in the social dominance status of crayfish.
pubmed:affiliation
Department of Biology, Georgia State University, Atlanta 30302-4010, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.