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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1997-3-18
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pubmed:abstractText |
Gitaloxin is a digitalis glycoside used for the same indications as digoxin and digitoxin. The successful outcome for a 2 1/2-year-old boy who accidentally ingested 3 mg of gitaloxin (100 times the normal therapeutic dose) is reported. At admission the child presented with irregular heart rhythm. He subsequently started vomiting, even after continuous gastric feeding. Only 48 h after ingestion of gitaloxin he became somnolent and developed bradyarrhythmia. The symptoms disappeared 96 h later; the bradyarrhythmia, however, (second-degree atrioventricular block) decreased progressively only after 120 h. The initial clinical presentation of gitaloxin poisoning may be misleading and careful observation in a pediatric intensive care unit is mandatory. A cross-reaction between the fluorescence polarization immunoassay for digitoxin and the radioimmunoassay for gitaloxin was found and was used as a helpful, but rough, estimate of the severity of gitaloxin poisoning, in the absence of a specific measurement of gitaloxin.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0342-4642
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1442-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8986501-Bradycardia,
pubmed-meshheading:8986501-Child, Preschool,
pubmed-meshheading:8986501-Digoxin,
pubmed-meshheading:8986501-Electrocardiography,
pubmed-meshheading:8986501-Fluorescence Polarization Immunoassay,
pubmed-meshheading:8986501-Humans,
pubmed-meshheading:8986501-Intensive Care,
pubmed-meshheading:8986501-Male,
pubmed-meshheading:8986501-Poisoning,
pubmed-meshheading:8986501-Vomiting
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pubmed:year |
1996
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pubmed:articleTitle |
Gitaloxin poisoning in a child.
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pubmed:affiliation |
Toxicology Department, University Hospital, Free University Brussels, Belgium.
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pubmed:publicationType |
Journal Article,
Case Reports
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