|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0006462,
umls-concept:C0023688,
umls-concept:C0205549,
umls-concept:C0220825,
umls-concept:C0243071,
umls-concept:C0289174,
umls-concept:C0379900,
umls-concept:C0549193,
umls-concept:C0598631,
umls-concept:C1415803,
umls-concept:C1516240,
umls-concept:C1521761,
umls-concept:C1621296
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
1997-2-26
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|
pubmed:abstractText |
The lipophilicity of a series of buspirone related agents was studied by means of reversed-phase HPLC using an octadecylsilane stationary phase a mixture of aqueous solution of sodium phosphate and methanol as a mobile phase. Comparison of the measured capacity factors with log P values has shown very good correlations with regression correlation coefficients in the range of 0.994-0.996.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0031-7144
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
51
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
924-7
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
pubmed-meshheading:8985981-Buspirone,
pubmed-meshheading:8985981-Calibration,
pubmed-meshheading:8985981-Chemistry, Physical,
pubmed-meshheading:8985981-Hydrogen-Ion Concentration,
pubmed-meshheading:8985981-Indicators and Reagents,
pubmed-meshheading:8985981-Ligands,
pubmed-meshheading:8985981-Physicochemical Phenomena,
pubmed-meshheading:8985981-Receptors, Serotonin,
pubmed-meshheading:8985981-Serotonin Antagonists
|
|
pubmed:year |
1996
|
|
pubmed:articleTitle |
Buspirone analogues as ligands of the 5-HT1A receptor. II: Capacity factors as chromatographic parameter of lipophilicity evaluation in a series of 5-HT1A and 5-HT2A receptor ligands.
|
|
pubmed:affiliation |
Pharmaceutical Research Institute, Warsaw, Poland.
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|
pubmed:publicationType |
Journal Article
|
