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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1997-1-27
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pubmed:abstractText |
The optimal timing for collection of a single serum specimen to diagnose measles by using a monoclonal antibody-capture EIA was evaluated. Results of testing paired serum samples from 166 measles cases with at least 1 IgM-positive specimen were analyzed. Among persons whose second samples were IgM-positive, the seropositivity rate for first samples was 77% when collected within 72 h and 100% when collected 4-11 days after rash onset. Among unvaccinated persons whose first samples were IgM-positive, the rate for IgM positivity of second specimens declined from 100% at 4 days to 94% at 4 weeks after rash onset, then declined further to 63% at 5 weeks. Some previously vaccinated persons became IgM-negative during the third week after rash onset. In general, a single serum specimen collected between 72 h and 4 weeks after rash onset can be used to diagnose most cases of measles with an IgM capture EIA.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
175
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
195-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8985220-Adolescent,
pubmed-meshheading:8985220-Adult,
pubmed-meshheading:8985220-Antibodies, Viral,
pubmed-meshheading:8985220-Blood Specimen Collection,
pubmed-meshheading:8985220-Child,
pubmed-meshheading:8985220-Child, Preschool,
pubmed-meshheading:8985220-Humans,
pubmed-meshheading:8985220-Immunoenzyme Techniques,
pubmed-meshheading:8985220-Immunoglobulin M,
pubmed-meshheading:8985220-Infant,
pubmed-meshheading:8985220-Measles,
pubmed-meshheading:8985220-Measles Vaccine,
pubmed-meshheading:8985220-Measles virus,
pubmed-meshheading:8985220-Middle Aged,
pubmed-meshheading:8985220-Time Factors,
pubmed-meshheading:8985220-Vaccination
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pubmed:year |
1997
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pubmed:articleTitle |
Diagnosis of measles with an IgM capture EIA: the optimal timing of specimen collection after rash onset.
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pubmed:affiliation |
Department of Pediatrics, Emory University, Atlanta, Georgia, USA.
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pubmed:publicationType |
Journal Article
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