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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1997-1-7
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pubmed:abstractText |
In a randomized trial, we compared the efficacy and toxicity of azithromycin and ceftibuten once daily in the initial (empiric) therapy of proven or suspected community-acquired respiratory tract infections (CARTI) in 163 pediatric patients: 95.5% of those treated with azithromycin and 83.6% of those treated with ceftibuten were cured or improved. Streptococcus pneumoniae was more frequently eradicated in the azithromycin than in the ceftibuten group, whereas gram-negative bacilli were more susceptible to ceftibuten. Elimination rates for Staphylococcus aureus and Haemophilus influenzae were similar; adverse reactions did not differ in both arms. Thus, azithromycin was more effective but equally safe than ceftibuten in the initial therapy of pediatric CARTI.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0009-3157
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pubmed:author |
pubmed-author:DanisovicovaAA,
pubmed-author:DurcanskaKK,
pubmed-author:GalovaKK,
pubmed-author:GrausovaSS,
pubmed-author:HrachovaII,
pubmed-author:KrcméryVVJr,
pubmed-author:KrizanSS,
pubmed-author:KrupovaII,
pubmed-author:KukovaZZ,
pubmed-author:MarinovaII,
pubmed-author:RaskovaJJ,
pubmed-author:StahorskaAA,
pubmed-author:StopkovaKK,
pubmed-author:SufliarskaSS
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pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
231-4
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:8983893-Adolescent,
pubmed-meshheading:8983893-Anti-Bacterial Agents,
pubmed-meshheading:8983893-Azithromycin,
pubmed-meshheading:8983893-Cephalosporins,
pubmed-meshheading:8983893-Child,
pubmed-meshheading:8983893-Child, Preschool,
pubmed-meshheading:8983893-Community-Acquired Infections,
pubmed-meshheading:8983893-Drug Administration Schedule,
pubmed-meshheading:8983893-Drug Therapy, Combination,
pubmed-meshheading:8983893-Humans,
pubmed-meshheading:8983893-Respiratory Tract Infections
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pubmed:articleTitle |
Multicenter randomized study of two once daily regimens in the initial management of community-acquired respiratory tract infections in 163 children: azithromycin versus ceftibuten.
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pubmed:affiliation |
Fourth Department of Pediatrics, Postgraduate Medical School, Kosice, Slovak Republic.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Case Reports,
Multicenter Study
|