Linked Life Data

8981005

Source:http://linkedlifedata.com/resource/pubmed/id/8981005

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1997-3-20
pubmed:abstractText
The unstimulated and stimulated thyrocyte is able to produce more different cytokines in vitro than any other endocrine cell. Cytokines produced by thyrocytes may play a role in the local stimulation and maintenance of immune responses against autoantigens in the thyroid, in the modulation of goiter size in response to TSH, and in the clinical course of patients with thyroid tumors. This paper tries to summarize the results of relevant studies investigating cytokine production by thyrocytes. Although there is an agreement in published work that thyrocytes secrete a number of cytokines such as II-1, II-6, II-8 and TGF-beta in vitro it is unclear whether these factors are produced also by thyrocytes in vivo. By the example of GM-CSF in vitro secretion by stimulated anaplastic thyroid carcinoma cell lines and stimulated thyrocytes, the relevance of these findings during the clinical course of patients with anaplastic thyroid tumours is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0947-7349
pubmed:author
pubmed:issnType
Print
pubmed:volume
104 Suppl 4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
64-7
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Expression of cytokines in the thyroid: thyrocytes as potential cytokine producers.
pubmed:affiliation
Department of Internal Medicine III, University of Leipzig, Germany.
pubmed:publicationType
Journal Article, Review