rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
1997-2-28
|
pubmed:abstractText |
Serum levels of a cytokeratin 19 fragment, Cyfra 21-1, were measured using an immunoradiometric assay in 33 women before initial treatment and in 8 women with recurrent tumor. The serum level of Cyfra 21-1 was significantly increased in women with tumors of advanced stage (FIGO) and those with recurrence. The incidence of positivity for Cyfra 21-1 tended to increase with tumor spread. Compared with squamous cell carcinoma (SCC) antigen, the sensitivity of Cyfra 21-1 was comparable to that of SCC antigen. The serum level of Cyfra 21-1 and that of SCC antigen showed a positive correlation. While the use of the serum Cyfra 21-1 level may be limited in cervical cancer by its relatively low sensitivity, a combination assay of Cyfra 21-1 and SCC antigen may be useful in the diagnosis and follow-up of patients with cervical squamous cell carcinoma.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0378-7346
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
42
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
267-70
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8979101-Adult,
pubmed-meshheading:8979101-Aged,
pubmed-meshheading:8979101-Aged, 80 and over,
pubmed-meshheading:8979101-Antigens, Neoplasm,
pubmed-meshheading:8979101-Carcinoma, Squamous Cell,
pubmed-meshheading:8979101-Female,
pubmed-meshheading:8979101-Humans,
pubmed-meshheading:8979101-Immunoradiometric Assay,
pubmed-meshheading:8979101-Keratins,
pubmed-meshheading:8979101-Middle Aged,
pubmed-meshheading:8979101-Neoplasm Recurrence, Local,
pubmed-meshheading:8979101-Neoplasm Staging,
pubmed-meshheading:8979101-Peptide Fragments,
pubmed-meshheading:8979101-Serpins,
pubmed-meshheading:8979101-Uterine Cervical Neoplasms
|
pubmed:year |
1996
|
pubmed:articleTitle |
Serum levels of cytokeratin 19 fragments in cervical cancer.
|
pubmed:affiliation |
Department of Obstetrics and Gynecology, Oita Medical University, Japan.
|
pubmed:publicationType |
Journal Article
|