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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1997-1-27
|
| pubmed:abstractText |
We evaluated 56 consecutive patients with newly diagnosed lymphoma including 48 with non-Hodgkin's lymphoma (NHL) and 8 with Hodgkin's disease to determine the clinical and prognostic significance of magnetic resonance imaging (MRI) of the femoral marrow. MR images of the femoral marrow were obtained by the T1-weighted spin echo method and the short TI inversion recovery technique. Abnormal "positive" images were seen in 29 of the 56 patients (52%). All 17 patients with positive biopsy results showed abnormal images on their femoral marrow MRI. Three "positive" MRI patterns-scattered (72%), uniform (21%), and nodular (7%)-were observed. The overall survival of the patients with a positive MRI pattern was significantly poorer than that of patients with a normal pattern (P = .0129). Survival did not differ significantly according to MRI pattern. The 3-year survival rate in the patients with a normal MRI pattern was 89.9% and in the patients with a positive MRI pattern, it was 41.0%. This difference was statistically significant (P = .0279) when we evaluated only the patients with NHL. Patients with positive MRI patterns, but a normal bone marrow histology, showed a significantly shorter survival than those with a normal MRI pattern (P = .016). These results indicate that abnormal MR images of the femoral marrow are associated with a significantly poorer survival in patients with malignant lymphoma, regardless of histologic findings in the marrow.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0006-4971
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
89
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
286-90
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8978303-Adolescent,
pubmed-meshheading:8978303-Adult,
pubmed-meshheading:8978303-Aged,
pubmed-meshheading:8978303-Aged, 80 and over,
pubmed-meshheading:8978303-Bone Marrow,
pubmed-meshheading:8978303-Female,
pubmed-meshheading:8978303-Femur,
pubmed-meshheading:8978303-Humans,
pubmed-meshheading:8978303-Lymphoma,
pubmed-meshheading:8978303-Magnetic Resonance Imaging,
pubmed-meshheading:8978303-Male,
pubmed-meshheading:8978303-Middle Aged,
pubmed-meshheading:8978303-Prognosis,
pubmed-meshheading:8978303-Retrospective Studies,
pubmed-meshheading:8978303-Survival Analysis
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Clinical and prognostic significance of femoral marrow magnetic resonance imaging in patients with malignant lymphoma.
|
| pubmed:affiliation |
Division of Hematology, Omiya Medical Center, Jichi Medical School, Saitama, Japan.
|
| pubmed:publicationType |
Journal Article
|