Linked Life Data

8970369

Source:http://linkedlifedata.com/resource/pubmed/id/8970369

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6 Pt 1
pubmed:dateCreated
1997-1-16
pubmed:abstractText
Neural diseases are often associated with respiratory muscle disorders. Assessment of the motor pathway from the central nervous system to the diaphragm is therefore highly clinically relevant from a diagnosis and follow-up point of view. Cortical magnetic stimulation (CxMS) combined with surface diaphragm electromyogram (EMGdi) has to date been limited in this application by the need of an underlying voluntary contraction to obtain a diaphragm response (facilitation). This study was performed to verify this point with high-powered stimulators and to describe the pattern of diaphragm response to CxMS. In nine subjects, EMGdi was compared with EMG of the abductor pollicis brevis (APB). CxMS was applied on relaxed muscles. The effects of its decreasing intensity and those of a voluntary contraction were studied. In three subjects, transdiaphragmatic pressure was also measured. CxMS consistently provoked a contraction of the relaxed diaphragm (16.06 +/- 0.64 ms, mean +/- SD). Decreasing stimulation intensity decreased the amplitude and increased the latency of this response. Underlying contractions had opposite effects. Respective behaviors of the diaphragm and APB were similar. It is concluded that CxMS gives access to central motor conduction to the diaphragm without the need for subject cooperation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1073-449X
pubmed:author
pubmed:issnType
Print
pubmed:volume
154
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1771-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Facilitation-independent response of the diaphragm to cortical magnetic stimulation.
pubmed:affiliation
Laboratoire de Physio-Pathologie Respiratoire, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't