| pubmed-article:8967419 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8967419 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:8967419 | lifeskim:mentions | umls-concept:C0000726 | lld:lifeskim |
| pubmed-article:8967419 | lifeskim:mentions | umls-concept:C1258215 | lld:lifeskim |
| pubmed-article:8967419 | lifeskim:mentions | umls-concept:C1704242 | lld:lifeskim |
| pubmed-article:8967419 | lifeskim:mentions | umls-concept:C0521390 | lld:lifeskim |
| pubmed-article:8967419 | lifeskim:mentions | umls-concept:C1704259 | lld:lifeskim |
| pubmed-article:8967419 | lifeskim:mentions | umls-concept:C1705987 | lld:lifeskim |
| pubmed-article:8967419 | lifeskim:mentions | umls-concept:C1314939 | lld:lifeskim |
| pubmed-article:8967419 | pubmed:issue | 4 Pt 2 | lld:pubmed |
| pubmed-article:8967419 | pubmed:dateCreated | 1996-12-4 | lld:pubmed |
| pubmed-article:8967419 | pubmed:abstractText | The 20-min rate of gastric emptying of a noncaloric solution and c-fos expression detected by immunohistochemistry in the brain were monitored 3 h after abdominal surgery performed under 10-min enflurane anesthesia in rats. Abdominal surgery (laparotomy and 1-min manipulation of the cecum) decreased gastric emptying from 60.8 +/- 3.4 to 25.9 +/- 3.4%. Capsaicin applied to the celiac/superior mesenteric ganglia 2 wk before the experiment reduced the delay in gastric emptying induced by abdominal surgery (46.3 +/- 3.4%), whereas perivagal capsaicin application had no effect (23.6 +/- 7.9%). The corticotropin-releasing factor (CRF) antagonist [D-Phe12, Nle21,38,C alpha MeLeu37]CRF-(12--41) injected intracisternally (10-20 micrograms) prevented postoperative gastroparesis induced by surgery, while having no effect on basal gastric emptying. Abdominal surgery increased the number of Fos-positive cells in brain nuclei regulating autonomic outflow: the nucleus of the solitary tract, locus ceruleus, paraventricular nucleus, and supraoptic nucleus of the hypothalamus. These data indicate that capsaicin-sensitive splanchnic afferent fibers and activation of CRF receptors in the brain are part of the neuronal circuitry mediating gastric stasis 3 h after abdominal surgery. | lld:pubmed |
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| pubmed-article:8967419 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8967419 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8967419 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8967419 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:8967419 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8967419 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:8967419 | pubmed:issn | 0002-9513 | lld:pubmed |
| pubmed-article:8967419 | pubmed:author | pubmed-author:RivierJJ | lld:pubmed |
| pubmed-article:8967419 | pubmed:author | pubmed-author:ZinnerM JMJ | lld:pubmed |
| pubmed-article:8967419 | pubmed:author | pubmed-author:TachéYY | lld:pubmed |
| pubmed-article:8967419 | pubmed:author | pubmed-author:MartinetLL | lld:pubmed |
| pubmed-article:8967419 | pubmed:author | pubmed-author:BonarJJ | lld:pubmed |
| pubmed-article:8967419 | pubmed:author | pubmed-author:BarquistEE | lld:pubmed |
| pubmed-article:8967419 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8967419 | pubmed:volume | 270 | lld:pubmed |
| pubmed-article:8967419 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8967419 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8967419 | pubmed:pagination | R888-94 | lld:pubmed |
| pubmed-article:8967419 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:8967419 | pubmed:meshHeading | pubmed-meshheading:8967419-... | lld:pubmed |
| pubmed-article:8967419 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8967419 | pubmed:articleTitle | Neuronal pathways involved in abdominal surgery-induced gastric ileus in rats. | lld:pubmed |
| pubmed-article:8967419 | pubmed:affiliation | Center for Ulcer Research and Education/Digestive Disease Research Center, West Los Angeles Veterans Affairs Medical Center, California, USA. | lld:pubmed |
| pubmed-article:8967419 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8967419 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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