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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1977-10-14
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pubmed:abstractText |
The digestion by DNAase I of DNA synthesised by isolated chicken erythroblasts was examined in isolated nuclei. It was found that newly synthesised DNA was susceptible to DNAase I but matured to a relatively resistant form with increasing time after replication as observed in mammalian systems. The presence of trypsin in the digestion exposed all of the DNA to DNAase I action. Examination of the digestion products showed that the newly replicated DNA differed little from the more mature form in the structure of the DNA-protein complex but that the difference in susceptibility was probably a result of a differential rate of access of the DNAase to the new and old DNA.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-1005118,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-1009941,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-1064026,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-10793712,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-1143324,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-1148184,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-1177305,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-1178528,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-13728117,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-15406373,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-4367431,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-4422492,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-4455255,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-4464857,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-4575957,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-4673369,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-4711166,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-5017428,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-5439512,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-765971,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-948749,
http://linkedlifedata.com/resource/pubmed/commentcorrection/896476-999696
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0305-1048
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1881-90
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:896476-Animals,
pubmed-meshheading:896476-Calcium,
pubmed-meshheading:896476-Cell Nucleus,
pubmed-meshheading:896476-Chickens,
pubmed-meshheading:896476-Chromatin,
pubmed-meshheading:896476-DNA,
pubmed-meshheading:896476-DNA Replication,
pubmed-meshheading:896476-Deoxyribonucleases,
pubmed-meshheading:896476-Erythroblasts,
pubmed-meshheading:896476-Erythrocytes,
pubmed-meshheading:896476-Magnesium,
pubmed-meshheading:896476-Thymidine,
pubmed-meshheading:896476-Time Factors,
pubmed-meshheading:896476-Trypsin
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pubmed:year |
1977
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pubmed:articleTitle |
Features of the structure of replicating and non-replicating chromatin in chicken erythroblasts.
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pubmed:publicationType |
Journal Article
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