Linked Life Data

8963677

Source:http://linkedlifedata.com/resource/pubmed/id/8963677

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1996-12-5
pubmed:abstractText
Groups of male Wistar rats lived in cages capable of monitoring feeding and drinking continuously at 0.1-s intervals, 24 h per day. Intact animals were subjected to 20 min of restraint stress or to brief handling (Brief Pick-Up), daily or every third day, 6 h after the beginning of the 12-h light period. In both studies, food-intake increased in the first hour after restraint, peaking between 15 and 45 min. Smaller increases were seen following Brief Pick-Up. More interestingly, the amount of food eaten increased across test sessions, indicating sensitization of the response to stress. Drinking also increased following stress, occurring before feeding and diminishing after the first 15 min. In adrenalectomized animals implanted with slow-release pellets to replace basal diurnal levels of corticosterone (ADX animals), sensitization of the feeding response to restraint stress developed across test sessions, although in these animals, the acute increase in food-intake following restraint stress was attenuated. ADX animals subjected only to Brief Pick-Up showed no increases in food-intake. Daily injections of 3.0 mg/kg corticosterone given to such ADX animals were unable to mimic the effects of restraint on either food-intake or drinking, nor did they augment the effects of restraint in ADX animals. We conclude that sensitization to the effects of brief restraint stress on food-intake can occur independently of a stress-induced rise in plasma corticosterone.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
26
pubmed:volume
710
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
35-44
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Sensitization of stress-induced feeding in rats repeatedly exposed to brief restraint: the role of corticosterone.
pubmed:affiliation
Department of Psychology, Concordia University, Montréal, Québec, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't