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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1997-3-7
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pubmed:abstractText |
Dendritic epidermal T cells (DETC) are skin-specific members of the epithelial gamma delta T-cell family that reside normally in murine epidermis. Recent studies indicate that certain cytokines (e.g. IL-2, IL-7 and IL-15) secreted by neighboring cells promote their residence and regulate their immune function. Conversely, DETC regulate the function of neighboring keratinocytes and Langerhans cells by elaborating other cytokines (e.g. interferon-gamma, keratinocyte growth factor and colony-stimulating factors). This reciprocal interaction represents a unique model of cytokine-mediated intercellular communication by tissue-specific gamma delta T cells with nearby epithelial and antigen presenting cells.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
1044-5323
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
333-9
|
pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8961384-Animals,
pubmed-meshheading:8961384-Cell Communication,
pubmed-meshheading:8961384-Cytokines,
pubmed-meshheading:8961384-Dendritic Cells,
pubmed-meshheading:8961384-Epidermis,
pubmed-meshheading:8961384-Humans,
pubmed-meshheading:8961384-Keratinocytes,
pubmed-meshheading:8961384-Langerhans Cells,
pubmed-meshheading:8961384-T-Lymphocyte Subsets
|
pubmed:year |
1996
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pubmed:articleTitle |
Cytokine-mediated communication by keratinocytes and Langerhans cells with dendritic epidermal T cells.
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pubmed:affiliation |
Department of Dermatology, University of Texas Southwestern Medical Center, Dallas 75235, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
|