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rdf:type |
|
|
lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1997-1-10
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pubmed:abstractText |
Patients with thyroid carcinoma experience excellent long-term survival; however, up to 16% will die of their disease. We have transformed a rat thyroid follicular cell line (FRTL-5) with a gene (TGCT) that mimics a known mutation associated with thyroid neoplasms. These cells form subcutaneous tumors that metastasize to lung in nude mice.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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|
pubmed:issn |
0039-6060
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
120
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
921-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8957474-Adenoviridae,
pubmed-meshheading:8957474-Adenoviridae Infections,
pubmed-meshheading:8957474-Animals,
pubmed-meshheading:8957474-Animals, Newborn,
pubmed-meshheading:8957474-Carcinoma,
pubmed-meshheading:8957474-Cell Death,
pubmed-meshheading:8957474-Cell Line, Transformed,
pubmed-meshheading:8957474-Feasibility Studies,
pubmed-meshheading:8957474-Ganciclovir,
pubmed-meshheading:8957474-Gene Expression,
pubmed-meshheading:8957474-Gene Therapy,
pubmed-meshheading:8957474-Humans,
pubmed-meshheading:8957474-Rats,
pubmed-meshheading:8957474-Simplexvirus,
pubmed-meshheading:8957474-Thymidine Kinase,
pubmed-meshheading:8957474-Thyroid Diseases,
pubmed-meshheading:8957474-Thyroid Gland,
pubmed-meshheading:8957474-Thyroid Neoplasms,
pubmed-meshheading:8957474-beta-Galactosidase
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pubmed:year |
1996
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|
pubmed:articleTitle |
Adenoviral infection of thyroid cells: a rationale for gene therapy for metastatic thyroid carcinoma.
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pubmed:affiliation |
Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Md., USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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