| pubmed-article:8956795 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8956795 | lifeskim:mentions | umls-concept:C0043210 | lld:lifeskim |
| pubmed-article:8956795 | lifeskim:mentions | umls-concept:C0678222 | lld:lifeskim |
| pubmed-article:8956795 | lifeskim:mentions | umls-concept:C0439234 | lld:lifeskim |
| pubmed-article:8956795 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:8956795 | pubmed:dateCreated | 1997-1-2 | lld:pubmed |
| pubmed-article:8956795 | pubmed:abstractText | One hundred and sixty-three breast carcinomas occurring in women aged between 26 and 44 years were examined for pathological features, oestrogen and progesterone receptor status, proliferation as determined by Ki-67 labelling and the presence of c-erbB-2 and p53 protein, and were compared with a control group of carcinomas from women in the 50-67 years age group. Carcinomas occurring in women aged under 35 years had a significantly high incidence of being poorly differentiated and of having high proliferation rates. This group also had a significantly high incidence of p53 protein staining. Carcinomas in the under 30 years age group had a lower incidence of oestrogen and progesterone receptor positivity. No differences were found in c-erbB-2-positive staining between the groups. Infiltrating lobular carcinomas were only identified in women aged 40 years and over. There was a higher incidence of a family history in the 35-44 years age group (18%) than in the under 35 years age group (11%). Breast carcinomas occurring in women aged under 35 years are more aggressive. An important finding is the high incidence of p53 positivity, which may indicate genetic instability. | lld:pubmed |
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| pubmed-article:8956795 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8956795 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8956795 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:8956795 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8956795 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:8956795 | pubmed:issn | 0007-0920 | lld:pubmed |
| pubmed-article:8956795 | pubmed:author | pubmed-author:WalkerR ARA | lld:pubmed |
| pubmed-article:8956795 | pubmed:author | pubmed-author:DearingS JSJ | lld:pubmed |
| pubmed-article:8956795 | pubmed:author | pubmed-author:LeesEE | lld:pubmed |
| pubmed-article:8956795 | pubmed:author | pubmed-author:WebbM BMB | lld:pubmed |
| pubmed-article:8956795 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8956795 | pubmed:volume | 74 | lld:pubmed |
| pubmed-article:8956795 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8956795 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8956795 | pubmed:pagination | 1796-800 | lld:pubmed |
| pubmed-article:8956795 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:8956795 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8956795 | pubmed:articleTitle | Breast carcinomas occurring in young women (< 35 years) are different. | lld:pubmed |
| pubmed-article:8956795 | pubmed:affiliation | Breast Cancer Research Unit, University of Leicester, Glenfield Hospital, UK. | lld:pubmed |
| pubmed-article:8956795 | pubmed:publicationType | Journal Article | lld:pubmed |
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